Iothalamic acid
Angio-conray, Conray, Cysto-conray, Vascoray (iothalamic acid) is a small molecule pharmaceutical. Iothalamic acid was first approved as Conray on 1982-01-01.
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Commercial
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Trade Name
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Glofil (discontinued: Angio-conray, Conray)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Iothalamate sodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| ANGIO-CONRAY | Mallinckrodt | N-013319 DISCN | 1982-01-01 | 1 products |
| CONRAY 325 | Mallinckrodt | N-017685 DISCN | 1982-01-01 | 1 products |
| CONRAY 400 | Mallinckrodt | N-014295 DISCN | 1982-01-01 | 1 products |
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Iothalamate meglumine
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Iothalamate sodium
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| VASCORAY | Mallinckrodt | N-016783 DISCN | 1982-01-01 | 1 products |
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Iothalamate sodium i-125
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| GLOFIL-125 | Iso-Tex Diagnostics | N-017279 RX | 1982-01-01 | 1 products |
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| conray | New Drug Application | 2023-05-11 |
| cysto-conray | New Drug Application | 2010-07-08 |
| cysto-conray ii | New Drug Application | 2020-12-31 |
| glofil-125 | New Drug Application | 2019-12-09 |
Indications
FDA
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Agency Specific
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertension | D006973 | EFO_0000537 | I10 | — | 1 | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Congenital abnormalities | D000013 | EFO_0003915 | Q89.9 | 1 | — | — | — | — | 1 |
| Neoplasms | D009369 | — | C80 | 1 | — | — | — | — | 1 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | — | — | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Kidney diseases | D007674 | EFO_0003086 | N08 | — | — | — | — | 4 | 4 |
| Renal insufficiency | D051437 | — | N19 | — | — | — | — | 2 | 2 |
| Kidney transplantation | D016030 | — | — | — | — | — | — | 1 | 1 |
| Sickle cell anemia | D000755 | EFO_0000697 | D57 | — | — | — | — | 1 | 1 |
| Liver failure | D017093 | — | K72.9 | — | — | — | — | 1 | 1 |
| Ischemia | D007511 | EFO_0000556 | — | — | — | — | — | 1 | 1 |
| Myocardial ischemia | D017202 | EFO_1001375 | I20-I25 | — | — | — | — | 1 | 1 |
| Chronic renal insufficiency | D051436 | — | N18 | — | — | — | — | 1 | 1 |
| Diagnosis | D003933 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Iothalamic acid |
| INN | iotalamic acid |
| Description | Iotalamic acid is an organic molecular entity. |
| Classification | Small molecule |
| Drug class | iodine-containing contrast media |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CNC(=O)c1c(I)c(NC(C)=O)c(I)c(C(=O)O)c1I |
Identifiers
| PDB | — |
| CAS-ID | 2276-90-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201300 |
| ChEBI ID | — |
| PubChem CID | 3737 |
| DrugBank | DB09133 |
| UNII ID | 16CHD79MIX (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Safety
Black-box Warning
Black-box warning for: Conray, Cysto-conray, Cysto-conray ii
Adverse Events
Top Adverse Reactions
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320 adverse events reported
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